sonicated thalamic neurons
I have a relative getting this done in a few weeks - it was FDA approved this summer.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812789/
we examined the effect of varying FUS sonication parameters on the excitation and suppression of region-specific cortical and deep (thalamic) brain regions in sheep.
I'll be hanging out with sheep soon - tomorrow.
Therefore, the FUS transducer with 30 mm focal depth (from the exit plane) was used to sonicate a localized brain region either ~10–23 mm or ~25–29 mm deep from the scalp using the coupling gels. The location of the acoustic focal point and corresponding sonication path with respect to the sheep’s head was visualized on the volumetric MRI data via spatial information acquired from the transducer tracker (using four infrared-reflective markers, in Fig 1D).
For assessment of suppressive effects, the suppressive FUS was delivered to the left S1 posterior to the CS or to the left thalamus, while measuring the SEP EEG induced by simultaneous external electrical stimulation of the right hind limb.
to see how it moves?
These parameter sets were chosen based on our previous investigations in small (rabbits and rats) and large animals (sheep) [4, 29–31, 65], in which a shorter sonication duration (≤ ~500 ms) at a higher DC (≥ 30%) favored excitation, and a longer sonication duration (≥ ~1 min) at a lower DC (≤ 10%) resulted in suppression.
OK just put on my blue light suppressing glasses to stop the retinal-blue light destruction of my retina....now I feel the burning sensation in the back of my eyeballs stopping...
monitoring the presence of overt muscle twitches or leg movement during sonication.
yep - see how it moves!!
So to treat a tremor then you want Suppression - not excitation. So longer lower DC ultrasound....
We found that the use of 15.8 W/cm2 Isppa generated a higher response rate than the use of a stronger Ia (18.2 W/cm2 Isppa) although this difference was not statistically significant in thalamic stimulation (Fig 3C)
How are they converting watts to ultrasound? So they use a piezoelectric transducer?
Of course our own Collagen are Piezoelectric transducers. I blogged before on how Coffee CAUSES essential tremor through dopamine damage of the neurons.
So I guess this treatment is supposed to just turn off the neurons all together - it's called a thalatomy like a lobatomy.
few sonication parameter sets (i.e., SP1 and SP3; tone-burst duration of 0.5 ms and Isppa of 5.4 W/cm2; acquired at 3 and 5% DCs) suppressed the SEP magnitude (18–35% reduction).
So that's the Suppression setting.
we applied pulsed sonication (at DCs of 3 or 5%) continuously for the duration of 2 min (i.e., F1 and F2) while delivering 50-μs electrical stimulations to the hind leg every 500 ms to elicit the SEP, with discrete EEG recording time windows.
So the 50-μs
is the wavelength of the ultrasound. So that is also phase coherence between the right and left ear! So we can detect sound phase difference at the ultrasound frequency but also at a FASTER rate than time-frequency uncertainty - which enables a quantum coherence via a metamaterial noncommutative resonance.
So when we do mind meditation as internal listening or internal focused emptying out of the I-thought - this creates an ultrasound resonance into quantum coherence as Yuan Qi.
But it's better to visualize light and turn the light around so you are working at the quantum coherence directly at the light frequency. That is the visualization tantra method of meditation - working with the intention of color transformation.
So then with the Standing active meditation - you utilize what they call in this study:
Contralateral.
versus Ipsilateral (same side).
16. Elias WJ, Huss D, Voss T, Loomba J, Khaled M, Zadicario E, et al. A pilot study of focused ultrasound thalamotomy for essential tremor. N Engl J Med. 2013;369(7):640–648. 10.1056/NEJMoa1300962 .
So since 90% of the collagen is piezoelectric along the vertical alignment then by standing you get a much strong pulse to ACTIVATE or Cultivate the energy.
Then by "suppressing" it through longer quiet meditation as inhibition - you are actually transducing the ultrasound into the higher frequency as quantum coherence as spirit meditation.
So that is called the Neti, Neti approach of Jnana meditation which then also became Buddhism.
OH the DC is Duty Cycle - not direct current. haha.
The creation of lesions in the ventral
intermediate nucleus of the thalamus or electrical
stimulation of the same region, which is part
of a large tremor circuit that integrates kinesthetic
and proprioceptive sensory information
from the cerebellum and spinal cord with the
cerebral cortex, are effective surgical interventions
for tremor,12-14 but many patients are reluctant
to undergo such invasive surgeries.
The use of ultrasound in the brain has been
of interest for decades.
I can FEEL and FLEX the center of my brain - to self-treat it with piezoelectric ultrasound.
Do we have collagen inside our brains? YES!
A powerful neuroprotector, collagen, specifically collagen VI, forms a barrier that protects the brain against amyloid-beta(Aβ), proteins that are widely believed to be the cause of Alzheimer's disease.
We found collagen XVII to be expressed widely in the brain and to be located primarily in the soma and proximal axons of neurons. In contrast, glial cells did not express collagen XVII.
so damage to the amygdala
This latter variable was a significant part of the linear model of the mean logarithmic power of the tremor harmonics, averaged over the AO, PO, and WE tasks, and normalized to RE task, in the hand with the more severe tremor. The time from onset variable was positively correlated with age, and negatively correlated with the left amygdala volume with respect to the intracranial volume.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482269/
Alpha frequency entrainment of motor regions by the amygdala would be an interesting mechanism to improve cognitive functions in PD patients suffering from dementia. However, inductions of oscillations at a specific frequency in the amygdala might require direct electrical stimulation, which has many drawbacks as discussed in the following section.
podcast interview
So instead of Newton's law of gravity try studying de Broglie's Law of Phase Harmony. The anti-gravity is from the negentropy or reverse time pressure energy of light. So when you meditation you build up negentropy that is stored in your body and your spirit can access negentropy when you "turn the light around" by visualization, etc. So your brain neurons are synchronized through meditation with the microtubules to access this universal negentropy energy aka dark energy or antigravity. It's Relativistic Quantum biology so most scientists don't know it - not because it's woo woo but rather because the CIA censors it! Professor Olivier Costa de Beauregard figured this out. It's also based on noncommutative phase math which is the opposite of the symmetric commutative math that Newton used. I have vid uploads on this on my youtube channel. thanks
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