Saturday, October 14, 2023

Then where else can you NOT go? Wim Hof new interview on the "Entrance Point" to immortality via the PAG

 https://www.youtube.com/watch?v=BE_U9LUKROU

periaqueductal gray hemisphere, cerebellum, inefferent and efferent electrical neural currents, 

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The periaqueductal gray is the gray matter located around the cerebral aqueduct within the tegmentum of the midbrain. It projects to the nucleus raphe magnus,... The ascending pain and temperature fibers of the spinothalamic tract send information to the PAG via the spinomesencephalic tract (so-named because the fibers originate in the spine and terminate in the PAG, in the mesencephalon or midbrain).

 Thermoreceptors can be separated into receptors for warmth and cold detection. According to results of differential nerve blocks and response latencies, the warmth sensation has been attributed to C fibers,...the existence of cold-sensitive C fibers has been suggested as the explanation of a heat-pain illusion occurring on simultaneous stimulation with non-noxious warm and cold

 Stimulation of the periaqueductal gray matter of the midbrain activates enkephalin-releasing neurons that project to the raphe nuclei in the brainstem. 5-HT (serotonin) released from the raphe nuclei descends to the dorsal horn of the spinal cord where it forms excitatory connections with the "inhibitory interneurons" located in Laminae II (aka the substantia gelatinosa). When activated, these interneurons release either enkephalin or dynorphin (endogenous opioid neurotransmitters), which bind to mu and kappa opioid receptors, respectively, on the axons of incoming C and A-delta fibers carrying pain signals from nociceptors activated in the periphery.

 Stimulation of the dorsal and lateral aspects of the PAG can provoke defensive responses characterised by freezing immobility, running, jumping, tachycardia, and increases in blood pressure and muscle tonus.

 The PAG may be specifically involved in human maternal behavior. The PAG contains a high density of vasopressin and oxytocin receptors,

 

 

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