In this case, the removal of the testicle causes the hypertrophy of the pineal gland.
Santamarina, E. (1958). MELANIN PIGMENTATION IN BOVINE PINEAL GLAND AND ITS POSSIBLE CORRELATION WITH GONADAL FUNCTION. Canadian Journal of Biochemistry and Physiology, 36(1), 227–235. doi:10.1139/y58-026
https://cdnsciencepub.com/doi/abs/10.1139/y58-026
It seems that the process of hypertrophy produced in the pineal gland by castration exhausts the gland far more within a short period of time than the exhaustion produced in the span of life.
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