Several members of that genus feature furin cleavage sites, which appear to have evolved repeatedly. And one SARS-CoV-2–related virus, described in a Current Biology paper last year by a team led by Shi Weifeng of Shandong First Medical University, has three of the four amino acids that constitute the furin cleavage site, which is “strongly suggestive of a natural zoonotic origin” for SARS-CoV-2, the authors concluded.
Call of the wild: Why many scientists say it’s unlikely that SARS-CoV-2 originated from a “lab leak”
A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein
https://www.sciencedirect.com/science/article/pii/S096098222030662X
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