Friday, April 17, 2026

Nine Light Skin Tone PGS are byproduct of last 8000 years of wheat farming diet lack of Vitamin D in Europe

 

 Selection for light skin tone at ten loci We found nine loci with genome-wide signals of selection for light skin tone, one probable signal and no loci showing selection for dark skin tone (Fig.%3h–q).

 https://reich.hms.harvard.edu/sites/reich.hms.harvard.edu/files/inline-files/2026_Akbari_Nature_selection_0.pdf

 One of the strongest signals is an increase over time in the PGS for light skin pigmentation (γ%=%1.80%±%0.10 standard deviations increase in mean PGS in ten millennia; P%=%5.7%×%10−74; Fig. 4 and Extended Data
Fig. 9). This plausibly reflects selection for increased synthesis of vitamin D in regions of low sunlight in farmers with little of it in their diets

  a PGS is a single numerical score that sums the effects of thousands or millions of different genetic variants (alleles)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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